-
Welcome to the CRISALIS website
The website has been redesigned for better visibility, with even more information and news!
Use the top-right Menu/Search button to discover the network, its areas of expertise and services, its research projects, information for patients and the media center. -
When asthma is well controlled, is it possible to stop a biologic without risk?
CRISALIS and Toulouse University Hospital launch WIDUSA, a large-scale national clinical study to answer an as yet unanswered question: can dupilumab (Dupixent® ), an expensive but highly effective treatment for severe asthma, be discontinued without worsening patients' health?
-
Asthma & obesity: the BOA study recruits patients!
Excess weight is known to worsen asthma symptoms and complicate asthma management. In obese patients, can weight reduction have a beneficial impact on asthma control? This is the question being investigated by the BOA study, which is recruiting in the Toulouse, Bordeaux and Montpellier University Hospital Centers, as well as in the Créteil Intercommunal Hospital Centre.
What is CRISALIS?
CRISALIS (Clinical Research Initiative in Severe Asthma: a Lever for Innovation & Science) is a national clinical investigation network specialized in severe asthma. Severe asthma is a rare and severe form of asthma that affects 3-6% of asthma patients. The unmet therapeutic needs in severe asthma are major and clinical research on this subject is highly justified. The CRISALIS network relies on collaborations between French clinicians and researchers specialized in severe asthma to facilitate this research and eventually improve patient care.
clinical research projects
CRISALIS has been involved in 27 research projects since its creation in 2018
institutionally-promoted projects
Out of 27 CRISALIS projects, 21 were carried out by institutional promoters
industrial partners
Companies involved in the network through partnerships, services, financial support
severe-asthma international publications linked to CRISALIS
this proportion is increasing
Network centres
16 member centers have been integrated into the CRISALIS network since its creation:
2018: 11 University Hospital Centers ("CHU") namely Toulouse, Nantes, Paris (AP-HP Bichat and Kremlin-Bicêtre), Lille, Strasbourg, Dijon, Lyon (HCL), Marseille (AP-HM Nord), Montpellier, Bordeaux
2019: Integration of Grenoble CHU
2020: Integration of Foch Suresnes Hospital
2021: Integration of Besançon CHU and Reims CHU
2022: Integration of Pointe-à-Pitre CHU (Guadeloupe)
CRISALIS also includes 25 partner centers: hospital centres, private hospitals, clinics... which have a privileged access to information about new severe asthma studies and network contacts
News
Press
F-CRIN
07 April 2026
News
F-CRIN
12 March 2026
